Dr. Carlos A. Portales Castillo (Medicine): A 30-year-old woman was admitted to this hospital because of headache and dysesthesia. The patient had been in her usual state of good health until 8 ...

Food and nutrition security exists when all people at all times have access to nutritious food for the prevention and treatment of disease and the promotion of health and well-being. Food and ...

We describe two patients in whom malignant monoclonal T-cell lymphoproliferation developed after administration of chimeric antigen receptor (CAR) T-cell therapy with ciltacabtagene autoleucel ...

Chemoimmunotherapy was the standard treatment for chronic lymphocytic leukemia (CLL), although it has now been largely replaced by targeted therapies. 1-3 Available targeted therapies include ...

Three of the authors served as editors-in-chief of MMWR: Dr. Rasmussen from 2015 to 2018, Dr. Lindegren from 2005 to 2006, and Dr. Altman from 1963 to 1964.Dr. Iademarco served as director of the ...

Familial HLH is a success story in modern medicine. Initially a disease that was largely unknown and fatal, it is now understood on a molecular level and is curable. Moreover, HLH is an archetype ...

Whether the large effect size of endovascular thrombectomy (EVT) for stroke due to large-vessel occlusion applies to stroke due to medium-vessel occlusion is unclear. In a multicenter, prospective ...

Malignant T-cell transformation after chimeric antigen receptor (CAR) T-cell therapy has been described, but the contribution of CAR integration to oncogenesis is not clear. Here we report a case ...

Dr. William J. Lu-Culligan (Medicine): A 41-year-old man was evaluated at this hospital because of swelling in both ankles and episodes of syncope. The patient had been in his usual state of ...

For decades, poor treatment options and low-quality evidence plagued care for patients with rifampin-resistant tuberculosis. The advent of new drugs to treat tuberculosis and enhanced funding now ...

Endovascular treatment (EVT) of stroke with large-vessel occlusion is known to be safe and effective. The effect of EVT for occlusion of medium or distal vessels is unclear. We randomly assigned ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...