Cancer Prevention Research publishes articles that focus on cancer prevention, preclinical, clinical, and translational research, with special attention given to molecular discoveries and an emphasis ...

Major Finding: Cancer cells transfer mitophagy-resistant mitochondria to tumor-infiltrating lymphocytes (TIL) that impair antitumor activity. Concept: Deubiquitinase USP30 protects cancer cell-derived ...

1Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota. *Corresponding Author: Jann N. Sarkaria, Department of Radiation Oncology, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905.

1Department of Radiation Oncology, Inselspital Bern University Hospital, Bern, Switzerland. 2Department for BioMedical Research, Radiation Oncology, University of Bern, Bern, Switzerland. 3Graduate ...

Main Finding: High-grade osteosarcomas frequently exhibit a loss–translocation–amplification (LTA) pattern of chromothripsis that inactivates TP53 and amplifies oncogenes. Concept: Ongoing ...

Trophoblast cell surface antigen 2 (TROP2) is a promising target for cancer therapy. Here, Li and colleagues present the preclinical evaluation of OBI-992, a TROP2-targeted antibody-drug conjugate ...

1Edwin L. Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. 2Department of Surgery, Keio ...

1Division of Clinical Pharmacology, LMU University Hospital, LMU Munich, Munich, Germany. 2German Cancer Consortium (DKTK), A Partnership Between LMU Hospital and DKFZ Heidelberg, Munich, Germany.

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. This work is licensed under a Creative Commons Attribution 4.0 International ...

The FDA’s Center for Drug Evaluation and Research issued its annual report on the approval of drugs, which announced that the agency OK’d 50 novel drugs in 2024, 15 of which were related to cancer ...

The U.S. National Science Foundation (NSF) announced that payments have been restored to the researchers who receive funding from the independent federal agency. Grant-recipients’ salaries were ...

1Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. 2The University of Texas MD Anderson Cancer Center, UTHealth Houston Graduate ...